Contents: • Anatomy • Physiology (Functions) • Splenic trauma • Splenomegaly 3. Spleen; The human spleen is located in the upper left abdomen, behind the stomach. The spleen is the largest secondary lymphoid organ in the body and, as such, hosts a wide range of immunologic functions alongside its roles in hematopoiesis and red blood cell clearance. 10. Similar in structure to a large lymph node, it acts primarily as a blood filter. • Wedge shaped 2. Many diseases and disorders of the spleen start with “Splen-” for example splenomegaly means enlargement of the spleen. Its long axis lies in the line of the tenth rib. The spleen is a dark red organ located in t WebMD's Spleen Anatomy Page provides a detailed picture, definition, and information about the spleen. Below is information about the structure and function of the canine spleen. Online quiz to learn Structure of the spleen; Your Skills & Rank. Histological structure of the spleen Stroma. The spleen is instead solely attached by its vascular pedicle and can become a wholly intraperitoneal hypermobile organ. Author: Maria Yiallouros, erstellt am: 2016/11/30, Editor: Maria Yiallouros, English Translation: PD Dr. med. Information on the anatomy of the spleen can be found on our sister website. Today 's Points. We will tell you about the general structure of the spleen, how the spleen works in dogs, common diseases that affect the spleen and common diagnostic tests performed in dogs to evaluate the spleen. One of us! The spleen is an organ found in virtually all vertebrates. Add to New Playlist. The structure of the spleen enables it to remove older erythrocytes from the circulation and leads to the efficient removal of blood-borne microorganisms and cellular debris. The spleen combines the innate and adaptive immune system in a uniquely organized way. The "stuff" is first the Capsule, indicated by the black arrows that covers the whole organ. Disturbance of spleen echostructure with or without splenomegaly. 0. Anatomy • The Splenic tissue develops from condensations of mesoderm in the dorsal mesogastrium. Loading ... Add to tournament . A rich branching network of trabeculae from the internal capsular surface subdivides the organ into communicating compartments. There is stuff all mixed up together. The spleen is the largest lymphatic organ in the body. Rarely, a normal spleen may be seen in the left upper quadrant, and an accessory spleen may be mobile and wander. Structures entering and leaving spleen at hilum: Splenic artery (branch of celiac artery) Splenic vein (branch of portal vein) Lymph vessels (efferent) Nerves; Blood moving through the spleen flows in sinusoids which contain distinct pores between endothelial cells. 2. The histological structure corresponds to that of the main spleen. An introduction to the histology of the spleen, as presented by the University of Rochester Pathology IT Program The marginal zone contained large … The spleen is the largest organ of the lymphatic system.Located in the upper left region of the abdominal cavity, the spleen's primary function is to filter blood of damaged cells, cellular debris, and pathogens such as bacteria and viruses.Like the thymus, the spleen houses and aids in the maturation of immune system cells called lymphocytes. Spleen. In many instances, the spleen enlarges as it performs its normal functions. Spleen tyrosine kinase is considered an attractive drug target for the treatment of allergic and antibody mediated autoimmune diseases. If there are clearly delimited anehogenic formations with distal acoustical amplification, it is necessary to differentiate: Polycystic (cysts may be multiple). Whereas the spleen growth was limited compared to the body growth in embryonic stages, the relative spleen weight increased 2.8 fold during the first 4 weeks post-hatching in quail. structure of Spleen (2) This a low power image of the Spleen. Add to Playlist 3 playlists. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Many diseases and disorders of the spleen start with “Splen-” for example splenomegaly means enlargement of the spleen. The spleen is divided by function and structure into the red pulp (RP) and white pulp (WP); in between these two regions is the marginal zone (MZ) in rodents and the perifollicular zone in humans (1, 2). We will tell you about the general structure of the spleen, how the spleen works in dogs, common diseases that affect the spleen and common diagnostic tests performed in dogs to evaluate the spleen. The structure of the spleen enables it to remove older erythrocytes from the circulation and leads to the efficient removal of blood-borne microorganisms and cellular debris. Spleen • situated principally in the left hypochondriac region, but its superior extremity extends into the epigastric region 3. The spleen is the largest single mass of lymphatic tissue in the body. Start studying 9. Structure of the spleen. Since the time of Hippocrates, it is believed that the spleen in the human body has a number of important functions. The WP is the primary immunologic region of the spleen in both species; however, the WP makes up less than a quarter of splenic tissue. Add to favorites 1 favs. The spleen is an organ the size of a fist found in the left upper quadrant (LUQ) of the abdomen, under the protection of the inferior thoracic cage. The white pulp was characterized by the presence of large numbers of lymphatic nodules containing highly reactive germinal centers. The structure of the spleen enables it to remove older erythrocytes from the circulation and leads to the efficient removal of blood-borne microorganisms and cellular debris. The spleen is surrounded by a thin capsule covered by peritoneum (mesothelial cells). Below is information about the structure and function of the canine spleen. This function, in combination with a highly organized lymphoid compartment, makes the spleen the most important organ for antibacterial and antifungal immune reactivity. First of all notice how the over all organization of the spleen looks like a BIG MESS. You need to get 100% to score the 10 points available. It is attached to the greater curvature of the stomach by the gastrosplenic ligament. In principle, the presence of an accessory spleen does not represent any health risks. The spleen is soft, highly vascular and dark purple in colour. Full text Full text is available as a scanned copy of the original print version. The pathologic process also may be acquired as a result of splenomegaly or ligamentous laxity, such as in pregnancy or muscular dystrophies. Rauscher spleen focus-forming virus contains functional gag and pol genes and a partially deleted env gene which is structurally related to the env genes of dual tropic murine leukemia viruses. The physical organization of the spleen allows it to filter blood of pathogens and abnormal cells and facilitate … Structure and function of the immune system in the spleen Sci Immunol. Structure and function of the lymphatic system. Gesche Tallen, Last modification: 2016/12/06 Table of contents. View as Printable Worksheet. Structure. This function, in combination with a highly organized lymphoid compartment, makes the spleen the most important organ for antibacterial and antifungal immune reactivity. The spleen is located in the upper left abdominal cavity, just beneath the diaphragm, and posterior to the stomach.It is similar to a lymph node in shape and structure but it is much larger. It sounds funny but, that is one way to remember the spleen. The spleen is enclosed in a capsule of fibrous and elastic tissue that extends into the parenchyma as trabeculae. Structure of the spleen in idiopathic thrombocytopenic purpura. It is multi-functional and to accommodate for this, it is a soft, vascularised organ with a fibro-elastic capsule. Get started! Location and Structure of Spleen: Spleen lies in between the fundus of the stomach and the diaphragm. The word spleen comes from Ancient Greek σπλήν (splḗn). Structure and function of Spleen 1. Learn about its function, location in the body, and conditions that can affect the spleen. Normal Ultrasound (Equine) Histological section ©Nottingham Uni 2008 : The spleen lies vertically on the left side of the cranial abdomen. Game Points. 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