Pufferfish is ranked amongst the topmost poisonous fish found till the present date. This lizard may not have fangs, but this rare lizard chews on a victim until its venomous saliva journey’s through its grooved teeth and into the wound it has formed. The animals we are looking at here are all venomous and actively inject their toxins. The tetrodotoxin poison affects the brain and may cause weakness, paralysis and death even at a minimum consumption of the poison, which makes it a highly dangerous fish. Scientists have focused a great deal of attention of venom produced by snakes and spiders, but venomous fish had been largely neglected, said … The Florida Fish and Wildlife Conservation Commission, nor any other organization, does not track the lizard's population statistics. There are not any known "venomous" lizards in Florida at this time, at least according to the definition of what "venomous" actually means, however, some of the state's nuisance lizards do have a toxic saliva that can be transmitted via bites and handling. ... Perhaps the most venomous lizard to humans is the Gila Monster of the Mexico / US deserts. These fish are named for their distinctively toothy appearance, which is rather lizardlike, especially when combined with the cylindrical bodies of many lizardfish species. This Distribution. Venom is a secretion containing one or more toxins produced by an animal. Venom has evolved in a wide variety of animals, both predators and prey, and both vertebrates and invertebrates.. Venoms kill through the action of at least four major classes of toxin, namely necrotoxins and cytotoxins, which kill cells; neurotoxins, which affect nervous systems; and myotoxins, which damage muscles. The inshore lizardfish is widely distributed. In humans, a single bite causes severe pain, swelling, falling blood pressure, sweating, and very rarely, death by respiratory failure. The fish has poison reservoir of tetrodotoxin in its liver, ovaries, intestines and skin. Based upon current research results, the world's most venomous lizard is the Gila monster Heloderma suspectum, native to the southwestern USA and northwestern Mexico.LD50 (lethal dose) values for its venom as low as 0.4 mg/kg have been recorded when administered intravenously in mice. Snakes: There are currently 13 recognized species of rattlesnakes in Arizona (17 in the US and about 36 species worldwide). A lizardfish is a fish in the family Synodontidae. The scientific and veterinary communities, meanwhile, remain divided on this issue. So, animals such as the poison dart frogs and puffer fish posses some of the most lethal toxins in nature but are poisonous, not venomous. 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